Notes on AI startups

By David Wu

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PERSONALIZESOON

Customized AI model for each enterprise

Oct 2026

1 note

Chart placing kinds of work by how easily results can be graded and how much money is at stake

LEARNOCT 2026 · 7 MIN

To scale self-improving AI startups, build the grader first

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Sep 2026

1 note

Calibration chart comparing a calibrated and an overconfident simulation

LEARNSEP 2026 · 7 MIN

To scale simulation AI startups, prove the calibration first

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Aug 2026

1 note

Agent requests converging on one default gateway

LEARNAUG 2026 · 9 MIN

To scale AI infrastructure startups, become the default first

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AI agents I've built

Solving what's been unsolvable in clinical trials — redefining what's achievable.

CoTrial AI · Clinical-trial intelligence agent for CROs

2025 · FOUNDER AND HEAD OF PRODUCT · VISIT ↗

David Wu

David Wu

Ex-Founder, CoTrial AI | Head of Product